The Blacklist: The Blacklist' follows Raymond "Red" Reddington (James Spader), one of the FBI's most wanted fugitives, as he joins with the FBI, claiming that they can work with one another. When he agrees to cooperate in bringing down dangerous criminals and terrorists, he tells them that he will only speak with Elizabeth Keen (Megan Boone), a rookie FBI profiler.
As they work together, Keen questions Reddington's motives and Reddington simply feels she is very special. When one terrorist is taken down, Reddington informs them that it is only the beginning. Reddington gives the FBI access to "The Blacklist", a list with known terrorists and criminals the world doesn't know about. With Reddington's help, they work together to eradicate the list.